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Sayed K Goda Selected Research

gamma-Glutamyl Hydrolase (Carboxypeptidase G2)

2/2020In vitro studies on CNGRC-CPG2 fusion proteins for ligand-directed enzyme prodrug therapy for targeted cancer therapy.
4/2019Production of "biobetter" variants of glucarpidase with enhanced enzyme activity.
1/2019Production of "biobetter" glucarpidase variants to improve drug detoxification and antibody directed enzyme prodrug therapy for cancer treatment.
1/2018Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment.
12/2009Functional overexpression and purification of a codon optimized synthetic glucarpidase (carboxypeptidase G2) in Escherichia coli.

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Sayed K Goda Research Topics

Disease

10Neoplasms (Cancer)
12/2021 - 12/2009
1Hypotension (Low Blood Pressure)
07/2019
1Sepsis (Septicemia)
07/2019
1Leukemia
03/2014
1Homocystinuria
01/2010

Drug/Important Bio-Agent (IBA)

7Pharmaceutical PreparationsIBA
12/2021 - 12/2009
6ProdrugsIBA
01/2021 - 12/2009
6EnzymesIBA
01/2021 - 12/2009
5gamma-Glutamyl Hydrolase (Carboxypeptidase G2)IBA
02/2020 - 12/2009
4Proteins (Proteins, Gene)FDA Link
12/2021 - 01/2010
4LigandsIBA
12/2021 - 02/2020
4Methotrexate (Mexate)FDA LinkGeneric
02/2020 - 12/2009
4glucarpidaseIBA
04/2019 - 12/2009
2Peptides (Polypeptides)IBA
12/2021 - 07/2019
2AntigensIBA
12/2021 - 07/2019
2ZD 2767IBA
01/2021 - 02/2020
2CD13 Antigens (Alanine Aminopeptidase)IBA
01/2021 - 02/2020
2CytokinesIBA
05/2020 - 07/2019
2SuperantigensIBA
05/2020 - 07/2019
1IntegrinsIBA
12/2021
1Carcinoembryonic AntigenIBA
12/2021
1Nanoparticle Drug Delivery SystemIBA
12/2021
1Folic Acid (Vitamin M)FDA LinkGeneric
12/2021
1GoldIBA
12/2021
1Hepatitis B e AntigensIBA
12/2021
1Somatostatin Receptors (Somatostatin Receptor)IBA
12/2021
1Immune Checkpoint InhibitorsIBA
05/2020
1Cysteine (L-Cysteine)FDA Link
02/2020
1DisulfidesIBA
02/2020
1asparagine-glycine-arginineIBA
02/2020
1EpitopesIBA
01/2018
1ethyl 3- (2- ((tert- butylamino)- 1- (N- (4- chlorobenzyl)formamido)- 2- oxoethyl)- 6- chloro- 1H- indole- 2- carboxylateIBA
03/2014
1Carboxylic AcidsIBA
03/2014
1EstersIBA
03/2014
1Methionine (L-Methionine)FDA Link
01/2010
1Cystathionine beta-Synthase (Serine Sulfhydrase)IBA
01/2010
1Caseins (Casein)FDA Link
01/2010

Therapy/Procedure

9Therapeutics
12/2021 - 12/2009
1Precision Medicine
05/2020
1Immunotherapy
07/2019